Schizophrenia Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 65 years old who have been diagnosed with a schizophrenia spectrum disorder (such as schizophrenia, schizoaffective disorder, or a related psychotic disorder) based on standard diagnostic criteria (DSM-5)
• People whose treating psychiatrist considers them to be in a clinically stable condition
• People whose antipsychotic medication has stayed the same for at least 4 weeks
• People who have not been admitted to an acute psychiatric ward in the 3 months before joining the study
• People who are able to give informed consent, as assessed by their treating psychiatrist, and who have signed a consent form

Who may not be able to join:

• People currently experiencing an active major depressive episode, as determined by their treating psychiatrist
• People currently experiencing active psychotic symptoms, such as delusions, hallucinations, or feelings of persecution above a certain severity level on a standard rating scale
• People with significant movement-related side effects from medication, above a certain threshold on a standard assessment scale
• People experiencing notable sedation from medication, such as drowsiness, slowed thinking, or slurred speech
• People who are actively using substances on a daily basis (such as cocaine), including certain medications used as substitution therapy (such as methadone)
• People with a history of unexplained fainting episodes that may have been seizures
• People with a history of multiple seizures or a diagnosis of epilepsy
• People with a progressive neurological condition such as multiple sclerosis or Parkinson's disease
• People with chronic uncontrolled medical conditions that could become dangerous if a seizure were to occur (such as certain heart conditions or severe asthma)
• People with metal objects or implants in their body, unless those implants have been confirmed to be safe for MRI scanning
• People with certain implanted medical devices in or near the head, including pacemakers, implanted medication pumps, vagal nerve stimulators, deep brain stimulators, TENS units, ventriculo-peritoneal shunts, or cochlear implants
• People with a reduced ability to feel heat or pain, or who have open wounds
• People with increased pressure inside the skull
• People with brain lesions caused by a genetic condition, stroke, tumour, cerebral palsy, severe head injury, or significant brain structural differences
• People with a history of a head injury that caused loss of consciousness for more than 15 minutes, or that led to lasting neurological effects
• People who are currently pregnant or breastfeeding; people who could become pregnant would need to be using active contraception to be considered for enrolment
• People with other significant ongoing medical conditions such as kidney failure, liver dysfunction, serious heart disease, cancer, or severe lung disease
• People who are unable to follow study procedures due to language barriers, psychological difficulties, intellectual disability, or dementia
• People who are under a legal obligation for psychiatric treatment
• People who have taken part in another clinical trial involving an investigational drug or medical device in the 30 days before this study, or who are currently in another trial
• People who have previously been enrolled in this same study
• The principal investigator running the trial, along with their family members, employees, or other people who depend on them

Important: Always verify eligibility with the trial site directly before applying.