Macular Degeneration Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 55 and 99 years old.
• People who have a specific type of eye condition called complete RPE and outer retinal atrophy (cRORA) — this is a particular pattern of damage to a layer at the back of the eye, confirmed through detailed eye imaging (confirm with trial site for exact measurements required).
• If both eyes meet the criteria, both eyes may be included in the study.
• People whose eyes are clear enough (no clouding of the lens or other obstructions) and whose pupils can be dilated sufficiently for imaging and vision testing.

Who may not be able to join:

• People who have had eye surgery in the study eye within the 3 months before the study starts.
• People who have previously received anti-VEGF injections (a type of eye injection treatment) in the study eye.
• People who have a history of a specific type of swelling in the eye after cataract surgery (known as pseudophakic cystoid macular edema or Irvine Gass Syndrome) in the study eye.
• People who have uncontrolled glaucoma in the study eye, meaning eye pressure has remained high (25 mmHg or above) even with pressure-lowering medication, or where a certain measurement of the optic nerve exceeds a specific threshold (confirm with trial site).
• People who have another eye condition in the study eye that the study doctor believes is likely to need medical or surgical treatment during the study to prevent vision loss.
• People who have another eye condition in the study eye that the study doctor believes could interfere with the study results or require surgery (other than cataract surgery or a specific laser procedure called YAG capsulotomy).
• People who have corneal damage, cloudiness, or scarring in the study eye that affects their best corrected vision.
• People with a refractive error (the degree of short- or long-sightedness) greater than 6 diopters — this also applies to people who have had cataract surgery or refractive surgery if their prescription history exceeded 6 diopters.
• People currently taking medications known to damage the retina, such as hydroxychloroquine or tamoxifen.
• People who have active abnormal blood vessel growth at the back of the eye (macular neovascularization) at the time of study entry.

Important: Always verify eligibility with the trial site directly before applying.