Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are willing to take part voluntarily and are able to sign a consent form after understanding what the study involves.
• You are 18 years of age or older.
• You have been diagnosed with advanced or metastatic non-small cell lung cancer (a type of lung cancer that has spread or cannot be removed by surgery), and your cancer has a specific genetic change called an ALK fusion mutation, confirmed by testing.
• Your doctor expects you to live for more than 12 weeks.
• Your blood counts, organ function, heart health, and other lab results are at acceptable levels as assessed by the study doctor.
• You are able to swallow tablets or capsules by mouth.
• If you are a woman who could become pregnant, you are willing to use appropriate birth control and not breastfeed from the time you sign the consent form until 6 months after your last dose of study medication.
• If you are a man, you are willing to use a condom from the time you sign the consent form until 6 months after your last dose of study medication.
• If you are a woman, you either have a negative blood pregnancy test within 3 days before joining, or you can confirm you are not at risk of pregnancy (for example, you are postmenopausal or have had surgery such as removal of the uterus or ovaries — confirm with trial site).

Who may not be able to join:

• You have taken certain medications in the past 7 days that strongly affect how the body processes drugs (called strong CYP3A4 inhibitors or inducers), and you would need to continue taking them during the study (confirm with trial site).
• You have an active infection such as active hepatitis B, hepatitis C, or HIV — though people managing hepatitis B or C with oral antiviral tablets may still be eligible (confirm with trial site).
• You have another serious illness, abnormal test result, or health condition that the study doctor believes makes it unsafe for you to take the study drug or could affect the study results.
• You are pregnant, currently breastfeeding, or planning to become pregnant during the study.
• You have a known allergy or sensitivity to lorlatinib (the study drug) or any of its ingredients.
• The study doctor believes for any reason that you may have difficulty following the study's procedures and requirements.

Important: Always verify eligibility with the trial site directly before applying.