Phase 2 Prostate Cancer Trial, Recruiting NCT06378346 Sponsor: University of Illinois at Chicago Condition: Prostate Cancer
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Phase 2 Prostate Cancer Trial, Recruiting

NCT06378346
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older at the time of signing consent
  • People whose general health and ability to carry out daily activities falls within an acceptable range as rated by a standard medical scale (ECOG score of 0, 1, or 2)
  • People who have been diagnosed with prostate cancer confirmed by tissue testing
  • People whose surgical team has assessed them as suitable for an operation to remove the prostate (radical prostatectomy)
  • People who are able to sign a written consent form and agree to the release of personal health information as approved by the relevant review board
  • People who are willing to use a barrier method of contraception (such as a condom) throughout the study treatment period

Who may not be able to join:

  • People who have another cancer (past or current) that the treating specialist believes could interfere with the safety or results of this study
  • People who have received chemotherapy, radiation, hormone therapy, immunotherapy, or other cancer or experimental treatments within the 30 days before starting the study
  • People who are currently taking certain medications that strongly or moderately affect how the body processes a specific liver enzyme (CYP3A4), unless those medications have been stopped for at least one week before joining
  • People who are taking medications known to affect heart rhythm in a specific way (QT interval prolongation), or who have a history of a particular heart rhythm condition called Torsades de Pointes, or who have poorly controlled high blood pressure, low potassium or magnesium levels in the blood, slow digestion, or reduced activity of a specific enzyme involved in hormone processing (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Natalie Reizine, University of Illinois at Chicago

Phone: 312-996-1581

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Illinois at Chicago
Registry
ClinicalTrials.gov
Start date
25 July 2024
Est. completion
1 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To evaluate anti-tumor activity of GLY by assessing changes in prostate-specific antigen (PSA) after GLY treatment administration and prior to radical prostatectomy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov