Phase 2 Ovarian Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You must be willing and able to sign a consent form agreeing to take part in the study.
- You must be 18 years of age or older when you sign the consent form.
- You must be fairly active and able to carry out daily activities with little or no limitation (this is measured by a standard scale called ECOG, scores 0 or 1 — confirm with trial site).
- You must have already received at least one previous treatment for your cancer.
- Your cancer must have been confirmed to have a specific gene change called a TP53 Y220C mutation (confirmed through testing).
- You must have at least one area of cancer in your body that can be measured on a scan.
- Your blood, kidney, liver, and clotting functions must be within acceptable levels based on blood tests.
- You must be able to swallow and digest tablets or capsules taken by mouth.
Who may not be able to join:
- You may not be eligible if your cancer has spread to the brain or spinal cord, or if you have a primary brain tumour.
- You may not be eligible if you have an active infection that requires treatment with medicines given into the vein or by mouth, within the past 7 days.
- You may not be eligible if you currently have active Hepatitis B or Hepatitis C infection.
- You may not be eligible if you have any serious or uncontrolled medical conditions (confirm with trial site).
- You may not be eligible if your heart's pumping function is below a certain level, as measured by a heart scan (confirm with trial site).
- You may not be eligible if a specific measurement of your heart's electrical activity is above a certain level, detected on a heart tracing (ECG) (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 781-918-6670
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Dose limiting toxicity (DLT); Number of participants with adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.