Schizophrenia Trial, Recruiting NCT06386588 Sponsor: Massachusetts General Hospital Condition: Schizophrenia
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Schizophrenia Trial, Recruiting

NCT06386588
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 18 and 45 years old
  • People who are fluent in English
  • People who are able to give their informed consent to participate

For people with schizophrenia, these additional criteria also apply:

  • People who have a confirmed diagnosis of schizophrenia according to DSM-V diagnostic standards
  • People who are either not taking antipsychotic medication, or who have been on a stable dose of antipsychotic medication for a consistent period

Who may not be able to join:

  • People who have ferrous (magnetic) metal anywhere in their body
  • People who are currently pregnant or breastfeeding
  • People who have physical difficulties with hand or finger movement that would prevent them from completing a finger-tapping task
  • People with an IQ below 85
  • People who have a neurological condition, including epilepsy or a seizure disorder
  • People who have significant hearing or vision loss
  • People who have a long-term medical condition that affects their sleep
  • People who have an unstable long-term medical condition, such as asthma, diabetes, cystic fibrosis, or heart disease
  • People who have a diagnosed sleep disorder, with the exception of insomnia
  • People who have a history of a head injury that caused an extended loss of consciousness or resulted in lasting neurological effects

For healthy adults (those without schizophrenia), these additional criteria also apply:

  • People with a history of mental illness
  • People currently taking psychiatric medications, or any medications known to affect sleep or cognition

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 617-702-2368

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
5 February 2025
Est. completion
30 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Changes in sleep physiology; Changes in functional connectivity of the hippocampus and thalamus; Changes in hippocampal activation during motor sequence task (MST); Changes in hippocampal microstructural integrity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov