Breast Cancer Trial, Recruiting NCT06388122 Sponsor: Mayo Clinic Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT06388122
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have hormone receptor-positive (HR+) breast cancer that has spread to other parts of the body (metastatic), and you are either pre- or post-menopausal.
  • You are in one of these situations:
    • Group 1: You are about to start your first treatment using one of three specific targeted drugs (palbociclib, ribociclib, or abemaciclib) combined with a hormone-blocking therapy.
    • Group 2: You are about to start a second or later round of treatment using one of those same targeted drugs, with or without a hormone-blocking therapy.
    • Group 3: You are already receiving your first treatment combining one of those targeted drugs with a hormone-blocking therapy.
    • Group 4: You are about to start, or are already receiving, a hormone-blocking therapy on its own (not combined with other drugs) as a first or second treatment.
    • Group 5: You have stage 2 or stage 3 HR+ breast cancer (not yet spread) and are about to start or are already receiving ribociclib or abemaciclib combined with a hormone-blocking therapy after surgery.
  • If you are already taking part in another clinical trial, you may still be able to join this study at the same time.

Who may not be able to join:

  • You are currently receiving an experimental or investigational treatment as part of another study (confirm with trial site).
  • Your breast cancer has been diagnosed at an early stage only (not metastatic or adjuvant stage 2/3).
  • You are a male with breast cancer.
  • You are currently being treated for another active cancer, unless it is a non-melanoma skin cancer or a very early-stage (non-invasive) cancer such as cervical or prostate carcinoma-in-situ.
  • You are unable to read and sign a consent form agreeing to take part in the study.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
30 April 2024
Est. completion
15 June 2031

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

DiviTum®TKa assay as an early predictor of primary treatment resistance

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov