Peripheral Arterial Disease Trial, Recruiting NCT06399900 Sponsor: Northwestern University Condition: Peripheral Arterial Disease
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Peripheral Arterial Disease Trial, Recruiting

NCT06399900
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 50 and older
  • People who have been diagnosed with peripheral artery disease (PAD) — a condition where reduced blood flow affects the legs — confirmed by one of the following: a specific blood pressure test in the ankle showing reduced flow, imaging evidence of a significant blockage (at least 70%) in an artery supplying the legs, or a borderline ankle pressure reading that drops noticeably after a heel-rise exercise test

Who may not be able to join:

  • People who have had an amputation of part or all of either leg
  • People with a very severe form of PAD that causes pain at rest, combined with very low blood flow readings
  • People who use a wheelchair full-time or need a walker to get around
  • People whose walking ability is limited by a condition other than PAD
  • People who currently have an ulcer (open sore) on the bottom of their foot
  • People who do not successfully complete the study's initial run-in period
  • People who have major surgery, or a procedure to open blocked arteries in the heart or legs, planned within the next four months
  • People who have had major surgery, a heart or leg artery procedure, or a major heart-related event within the previous three months
  • People with serious ongoing health conditions, including a lung disease requiring oxygen use during the day, Parkinson's disease, a life-threatening illness with a life expectancy of less than six months, or cancer that has required treatment within the past two years (confirm with trial site regarding exceptions for early-stage cancer with an excellent outlook, or oxygen needed only at night)
  • People who score below 23 on a standard memory and thinking assessment
  • People who do not speak English
  • People who have participated in or completed another clinical trial within the previous three months (specific waiting periods apply after stem cell, gene therapy, supplement, or drug trials — confirm with trial site)
  • People whose vision problems affect their ability to walk
  • People whose walking distance in a six-minute walk test falls below 400 feet or above 1,700 feet
  • People who have taken part in a supervised treadmill or cardiac rehabilitation exercise program in the past three months, or who plan to start one within the next five months
  • People who are not willing to avoid using red light therapy outside of the study
  • People whose resting blood pressure is below 100/45
  • People whom the trial investigator determines, at their discretion, may not be a safe or suitable fit for the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 13125036419

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
12 August 2024
Est. completion
30 September 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Six-Minute Walk Distance; Six-Minute Walk Distance

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov