Phase 3 Crohn's Disease and Colitis Trial, Recruiting NCT06405087 Sponsor: Takeda Condition: Crohn's Disease and Colitis
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Phase 3 Crohn's Disease and Colitis Trial, Recruiting

NCT06405087
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Treatment Group:

  • People who completed Week 34 of the related study (NCT06100289), showed a meaningful improvement in their condition by that point, and had not used corticosteroids for at least the 4 weeks before that visit
  • For those with ulcerative colitis (UC): improvement is measured using a scoring system that tracks stool frequency and rectal bleeding, with specific reductions required from the starting score (confirm with trial site for exact score details)
  • For those with Crohn's disease (CD): improvement is measured using a children's Crohn's disease activity score, with the score needing to be at or below a certain level and showing a meaningful drop from the starting score (confirm with trial site for exact score details)

Observation-Only Group:

  • People who received at least one dose of the study medication during the related study (NCT06100289) and either left that study early, or completed the Week 34 visit but were not eligible to join the Treatment Group of this trial

Who may not be able to join:

(Applies to the Treatment Group)

  • People who have a known allergy or sensitivity to vedolizumab or any of its ingredients
  • People who currently need, or are expected to need, major bowel surgery (such as bowel removal) during the course of this trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Study Director, Takeda

Phone: +1-877-825-3327

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
27 October 2025
Est. completion
12 August 2030

Where this trial is recruiting

🇧🇪 Belgium 🇧🇬 Bulgaria 🇩🇰 Denmark 🇮🇪 Ireland 🇮🇹 Italy 🇯🇵 Japan 🇳🇱 Netherlands 🇵🇱 Poland 🇵🇹 Portugal 🇷🇴 Romania 🇷🇸 Serbia 🇰🇷 South Korea 🇪🇸 Spain 🇨🇭 Switzerland 🇹🇼 Taiwan 🇺🇸 United States

Primary endpoints

Treatment Cohort: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs); Treatment Cohort: Number of Participants With Adverse Events of Special Interests (AESIs); Observational Cohort: Number of Participants With Prespecified Safety Events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov