Phase 2 Osteoarthritis Trial, Recruiting NCT06414473 Sponsor: University of Florida Condition: Osteoarthritis
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Phase 2 Osteoarthritis Trial, Recruiting

NCT06414473
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with knee osteoarthritis (a condition where the cartilage in the knee breaks down over time)
  • People who experience moderate to severe knee pain (rated 4 out of 10 or higher) during physical activity, in one or both knees

Who may not be able to join:

  • People who are pregnant (confirmed by a urine test) or currently breastfeeding
  • People who currently use cannabis products, including THC or CBD (confirmed by a urine drug screen)
  • People who have any existing or past medical condition that the trial investigators believe could affect their safety during the study (confirm with trial site)
  • People who have had a major surgery in the past 3 months, or who have an orthopaedic surgery planned during the study period that could affect their ability to report pain or quality of life
  • People who have taken part in another clinical trial involving an experimental drug within the past 3 months
  • People with a Body Mass Index (BMI) of 45 or above (a measure of body weight relative to height)
  • People who are currently taking certain medications that strongly affect how the body breaks down drugs (known as enzyme-modifying drugs) (confirm specific medications with trial site)
  • People with a history of suicidal thoughts or self-harm behaviour
  • People with a history of seizures or a traumatic brain injury
  • People with a history of liver or kidney disease
  • People with a history of heart or cardiovascular disease

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 352-294-1726

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
14 June 2024
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE); Theoretical Framework of Acceptability Questionnaire (TFAQ); Self-report Ratings of Knee Pain; Physical Activity; Western Ontario and McMaster Universities Arthritis Index (WOMAC)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov