Phase 2 study for people with Colorectal Cancer

Recruiting Phase 2

Sources: ClinicalTrials.gov Checked: 13 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 2
Sponsor Merck Sharp & Dohme LLC
Registry number NCT06428409
Started 20 June 2024 Today 16 October 2026 Estimated completion 16 October 2029

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Westmead Hospital ( Site 0003) Westmead NSW Active not recruiting
Royal Brisbane and Women's Hospital-Medical Oncology Clinical Trials Unit, Cancer Care Services ( Site 0001) Brisbane QLD Active not recruiting
Epworth Freemasons ( Site 0005) East Melbourne VIC Active not recruiting
Frankston Hospital-Oncology and Haematology ( Site 0004) Frankston VIC Active not recruiting
One Clinical Research ( Site 0002) Nedlands WA Active not recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 13 October 2026 · not medical advice

Who can join

Age 18 Years and over
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 220

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

The main inclusion criteria include but are not limited to the following:

* Has one of the following cancers:

* Unresectable or metastatic colorectal cancer and has received prior therapy for the cancer

* Advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) and has received prior therapy for the cancer

* Advanced and/or unresectable biliary tract cancer (BTC) and has received prior therapy for the cancer

* Advanced and/or unresectable BTC and has not received prior therapy for the cancer

* For participants who have received prior therapy for cancer: Has recovered from any side effects due to previous cancer treatment

Exclusion Criteria:

The main exclusion criteria include but are not limited to the following:

* History of severe eye disease

* For participants who have received prior therapy for cancer: Received prior systemic anticancer therapy including investigational agents within 4 weeks before starting study intervention

* History of (noninfectious) pneumonitis/interstitial lung disease (ILD) that required steroids, has current pneumonitis/ILD, or has suspected ILD or pneumonitis that cannot be ruled out by standard diagnostic assessments at Screening

Dates on the record

Started 20 June 2024
Estimated completion 16 October 2029
Registry last updated 6 October 2026
Checked by Voxsanity 13 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 6 October 2026.
  • This page last checked by Voxsanity: 13 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.