Phase 2 Asthma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older, male or female.
• You weigh at least 40 kg (approximately 88 lbs).
• You have been diagnosed with asthma (according to specific medical guidelines) and have had asthma for at least 1 year.
• You have been taking a medium or high dose inhaled asthma controller medication, plus at least one additional asthma controller medication, for at least 1 stable month before the study starts.
• You have had at least one asthma flare-up (worsening) in the past year while using medium or high dose inhaled asthma medication.
• Your blood test shows a certain minimum level of immune cells called eosinophils (confirm with trial site).
• Your lung function test results fall within a specific range, showing your breathing is partially but not severely reduced (confirm with trial site).
• If you are able to have children, you agree to avoid pregnancy and use highly effective contraception during the study and for a set period after the last dose.
• You are able and willing to sign a consent form before joining the study.

Who may not be able to join:

• You have another significant lung condition, such as an active lung infection, bronchiectasis, pulmonary fibrosis, or a history of lung cancer.
• You have a known problem with your immune system that causes it not to work properly.
• You have a serious, uncontrolled heart or blood vessel condition, such as a recent heart attack, unstable chest pain, heart failure, or stroke.
• You have had a significant flare-up of allergic rhinitis or sinus problems, or a notable infection (including respiratory infections), in the 4 weeks before the study starts.
• You have had a parasitic infection in the 6 months before the study starts.
• You have had a cancer diagnosis in the past 5 years (with some exceptions for certain fully treated skin or cervical cancers — confirm with trial site).
• You have donated blood, had a significant blood loss, or received blood products or immunoglobulins in the 4 weeks before the study starts.
• You have recently used certain immune-suppressing, immune-modifying, or biologic medications (such as specific antibody treatments or methotrexate) within a defined period before the study starts (confirm timing with trial site).
• You have taken part in another clinical trial and received an experimental treatment in the 30 days before the study starts.
• You have a planned surgery or other treatment during the study period that could affect the results.
• Your blood test results at the start of the study show significant abnormalities in areas such as white blood cell count, red blood cell levels, platelets, liver function, kidney function, or blood clotting (confirm with trial site).
• Your heart tracing (ECG) shows a specific abnormality or other results that may pose a safety risk (confirm with trial site).
• You have had a history of drug addiction or substance abuse in the past year.
• You are currently pregnant, breastfeeding, or plan to become pregnant during the study.
• You have a known allergy or bad reaction to anti-IL-5 antibody treatments or similar biologic medicines.
• The study doctor has another reason they consider makes it unsuitable for you to participate.

Important: Always verify eligibility with the trial site directly before applying.