Phase 3 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years old or older (there is no upper age limit)
- You have pain in an arm or leg that is focused enough to be fully covered by a nerve-blocking injection
- You have had this pain for at least 6 months
- You have had a stroke (either a bleed or a blockage in the brain) at least 6 months ago, confirmed by a brain scan (MRI)
- Your pain developed after your stroke and has been identified as nerve pain, based on a specific assessment tool called the DN4 (with a score of at least 4 out of 10)
- Your pain level is 4 or higher out of 10 on a pain scale at the time of joining and before each treatment session
- You are covered by a social security or health insurance scheme (this appears to be a French healthcare requirement — confirm with trial site)
- You have been on a stable painkiller routine for at least 2 weeks before joining
- You are willing and able to give your signed agreement to take part
Who may not be able to join:
- You are unable or unwilling to give your signed consent to take part
- You are under a legal protection order, such as guardianship or curatorship (confirm with trial site)
- You have an ongoing serious mental health condition (such as major depression or psychosis) or memory/thinking difficulties that would make it hard to follow the study or complete questionnaires
- Your pain is too widespread across a limb or side of the body to be fully covered by a nerve-blocking injection
- You are currently misusing drugs or other substances
- You have difficulty with language or understanding (for example, due to stroke-related speech problems), or you are unable to read
- You have moderate to severe kidney or liver problems
- You have a reason why local anaesthetic injections near a nerve would not be safe for you, such as an infection or inflammation at the injection site, or a known allergy to local anaesthetics
- You are pregnant or breastfeeding
- You have a known allergy to lidocaine, levobupivacaine, or similar local anaesthetic medicines
- You have a condition called recurrent porphyria, or you have severely low blood pressure that makes it unsafe to use the study medicines
- You are currently taking certain heart rhythm medications that cannot be stopped, which may interact with the study treatment (confirm specific medications with trial site)
- Your pain level drops below 4 out of 10 at the time of the nerve block sessions
- Your painkiller treatment needs to be changed at the start of or during the study
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 01 47 10 76 22
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To evaluate the efficacy of two peripheral nerve blocks performed 14 days apart on spontaneous neuropathic pain after stroke. The active treatments used for the blocks will be either lidocaine 20mg/ml or levobupivacaine 1.25mg/ml or placebo (saline)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.