Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are biologically female
• People who have been diagnosed with stage I, II, or III breast cancer
• People who were post-menopausal at the time of their breast cancer diagnosis, meaning their last menstrual period was at least 12 months before diagnosis
• People who have taken a type of hormone-blocking medication called aromatase inhibitors for 12 months or more in the past (not necessarily currently)
• People with a body mass index (BMI) of 25 or higher (confirm with trial site if unsure of your BMI)
• People who are willing and able to complete all study activities
• People who are able to travel to the University once per week for 24 weeks

Who may not be able to join:

• People who have received chemotherapy in the past 11 months
• People who have been diagnosed with cancer that has spread to other parts of the body (metastatic cancer), including if this happened after an early-stage breast cancer diagnosis
• People who are currently taking a hormone-blocking medication called tamoxifen
• People who are currently receiving chemotherapy, targeted cancer therapy, or radiation treatment
• People who have been diagnosed with heart disease, type 2 diabetes, non-alcoholic fatty liver disease, an uncontrolled thyroid condition, or a breathing condition such as severe asthma or COPD
• People who have significant symptoms that may suggest heart, diabetes, or kidney problems — such as chest pain, shortness of breath at rest or with light activity, dizziness or fainting, swollen ankles, irregular heartbeat, unusual leg pain when walking, a known heart murmur, or unusual tiredness with everyday activities
• People with certain serious heart or cardiovascular conditions that make supervised maximum-effort exercise testing unsafe, such as a recent heart attack, heart failure, blood clots in the lungs, heart inflammation, uncontrolled irregular heartbeat, stroke, very high blood pressure (above 200/100 mmHg), or a cancer diagnosis other than skin cancer (confirm with trial site for full list)
• People who are unable to give informed consent or communicate in English
• People who are currently pregnant or breastfeeding, or have been in the past 3 months
• People who have mobility limitations that affect their ability to do aerobic exercise, such as using a wheelchair, walker, or having a limp that affects walking
• People who have smoked cigarettes or marijuana in the past 3 months
• People who are currently taking or have taken hormone medications of any kind in the past 3 months
• People who cannot have a research MRI scan, for example due to a pacemaker or certain metal implants
• People with a BMI over 40
• People with severe claustrophobia (fear of enclosed spaces)
• People who are already doing more than 30 minutes per week of moderate-to-vigorous aerobic exercise
• People who have been following a diet that heavily restricts entire food groups or eating times in the past 3 months (such as vegan, ketogenic, carnivore, or one-meal-a-day diets)
• People who have lost more than 5 kg in weight in the past 3 months
• People who are currently taking weight loss medications
• People who have a diagnosed eating disorder, or who suspect they may have an undiagnosed eating disorder
• People who plan to be unavailable for more than 4 weeks total across the 6-month program, or more than 2 weeks during the first 12 weeks
• People who have an allergy to local anaesthetics

Important: Always verify eligibility with the trial site directly before applying.