Phase 2 Macular Degeneration Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are willing and able to read and sign a consent form agreeing to take part in the study
- You are a man or woman between 50 and 85 years old (inclusive) and have been diagnosed with wet age-related macular degeneration (wet AMD)
- You have previously been treated for wet AMD with anti-VEGF eye injections, your eye responded to that treatment, and you received at least 2 of these injections in the study eye in the 6 months before screening
- Your vision in the study eye (the eye being treated) falls within a specific range — roughly between 20/25 and 20/400 on a standard eye chart
- Your vision in your other eye meets a minimum level set by the study (confirm with trial site)
- If you are female, you must have gone through menopause at least 1 year ago
Who may not be able to join:
- Your study eye has a cause of abnormal blood vessel growth other than wet AMD, or another eye condition (such as diabetic eye disease or a blocked retinal vein) that could affect your central vision or eye examination results
- You have any condition in the study eye that would prevent your vision from improving, such as scarring, tissue hardening, or tissue loss in the central part of the retina
- You have a significant amount of bleeding under the retina in the study eye — either covering 50% or more of the affected area, or a larger bleed directly under the central part of the retina
- You have bleeding inside the gel-like fluid of the study eye, or have had this type of bleeding in the past
- You have an implant in the study eye (other than an artificial lens), or cloudiness or narrowing of the pupil that makes it difficult to examine the back of the eye
- You have a history of, or currently have, a detached retina or detached choroid (the layer beneath the retina) in the study eye
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +86176 0288 9310
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Tolerability and safety of KH658 in different dose levels; Change in BCVA letter
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.