Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older
• People who have had a stroke with a significant level of disability, measured by a standard stroke severity scoring tool (a score of 6 or more for strokes affecting the front of the brain, or 10 or more for strokes affecting the back of the brain)
• People where it is expected that they can be enrolled in the trial within 24 hours of when they were last known to be well
• People who have a blockage in one of several specific large blood vessels in the brain (the internal carotid artery, certain parts of the middle cerebral artery, the basilar artery, or a specific section of the vertebral artery)
• People whose blocked blood vessel has not reopened after up to three attempts at mechanical clot removal during a procedure to treat the stroke
• People where the treating doctor believes there is a high likelihood that the blockage is caused by hardening and narrowing of the arteries inside the brain (a condition called intracranial atherosclerotic disease)
• People whose blocked artery the treating doctor considers suitable for placement of a stent
• People who do not have a very large area of permanently damaged brain tissue, as assessed by a standard brain scan scoring method (a score of 6 or above on a specific scale used for strokes at the back of the brain)
• People who have given informed consent by signing the relevant forms, or where emergency consent procedures have been followed

Who may not be able to join:

• People who have active bleeding inside the brain
• People who had significant disability before the stroke, defined as a score of 3 or above on a standard disability scale
• People with serious known health conditions that would likely prevent recovery or attendance at follow-up appointments, such as cancer, dementia, or significant alcohol or drug misuse
• People with a known blood clotting disorder, or where an underlying condition causing the blood to clot too easily is suspected
• People whose stroke occurred while they were already in hospital
• People with known reasons why blood-thinning (anti-platelet) medications cannot be used
• People with a known serious allergic reaction to contrast dye used in imaging, or to nickel, titanium, or related metals (which may be present in a stent)
• People where attending follow-up appointments is unlikely to be possible due to geographic reasons, such as living overseas
• People who are known to be pregnant at the time of enrolment
• People whose brain scans show evidence of significant brain swelling caused by a mass, or a brain tumour (except for a small, non-concerning type called a meningioma)
• People whose brain scans show evidence of inflammation of blood vessels in the brain (cerebral vasculitis)
• People whose blocked blood vessel has already reopened before enrolment into the trial
• People who are already participating in another interventional clinical trial that could affect the results of this study

Important: Always verify eligibility with the trial site directly before applying.