Phase 3 Schizophrenia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 65 who have been diagnosed with Schizophrenia, Schizoaffective Disorder, or a related psychotic disorder.
• People who score above 35 on a symptom rating scale called the BPRS at the initial screening visit.
• People who score above 32 on an apathy rating scale called the AES-C at the initial screening visit.
• People whose current treatment plan (including any medications, supplements, or probiotics) has remained unchanged for at least 30 days before screening.
• People who, in the trial doctor's opinion, are able to attend all scheduled visits and are likely to complete all required assessments.
• People who speak and understand English, as all consent forms and assessments are conducted in English.
• People who are willing to take a urine drug screen and return a negative result.
• Women who could become pregnant must not currently be pregnant or breastfeeding, must have a negative urine pregnancy test, and must agree to use an accepted form of birth control (including abstinence) during the trial and for 30 days after the last dose of the study drug. This requirement also applies to men who could father a child.

Who may not be able to join:

• People who score below 35 on the BPRS rating scale at the screening visit.
• People who score below 32 on the AES-C rating scale at the screening visit.
• People with a significant medical condition or an unstable illness that, in the trial doctor's opinion, would prevent safe participation.
• People currently taking more than one antipsychotic medication.
• People currently receiving a long-acting injectable medication for psychotic symptoms.
• People with a substance use disorder, or whose urine drug screen shows a positive result for stimulants.
• Women who are pregnant or who could become pregnant without having measures in place to prevent pregnancy.
• People who have been diagnosed with dementia.
• People with an intellectual disability or level of cognitive difficulty that would, in the trial doctor's opinion, affect the ability to complete the symptom or apathy assessments.
• People who have been diagnosed with Parkinson's disease.

Important: Always verify eligibility with the trial site directly before applying.