Phase 1 Lymphoma Trial, Recruiting NCT06494371 Sponsor: Ruijin Hospital Condition: Lymphoma
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Phase 1 Lymphoma Trial, Recruiting

NCT06494371
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing to take part in the clinical research voluntarily
  • People aged between 18 and 75 years, of any sex
  • People with a general health and activity level that meets the study's requirements — a score of 0–1 during the dose-finding stage, or 0–2 during the dose-expansion stage (confirm with trial site what these scores mean for your situation)
  • People whose cancer has been confirmed by a tissue sample (biopsy) to be Hodgkin's lymphoma or Anaplastic large cell lymphoma, and whose cancer cells test positive for a protein called CD30
  • People who have at least one measurable area of cancer that can be tracked during the trial
  • People with an expected survival of at least 3 months
  • People whose blood test and other lab results fall within the ranges required by the study
  • People who are willing and able to use effective contraception during the trial

Who may not be able to join:

  • People who have recently received other cancer treatments and have not waited long enough since their last treatment (confirm with trial site what the required waiting period is)
  • People who have previously been treated with CAR-T cell therapy or a stem cell transplant from a donor
  • People with serious underlying health conditions (confirm with trial site for specific details)
  • People who test positive for Hepatitis B surface antigen, active Hepatitis B virus, active Hepatitis C virus, or HIV antibodies
  • People with other significant existing medical conditions that, in the treating doctor's judgement, would make participation in the study inappropriate

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 13524488296

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Registry
ClinicalTrials.gov
Start date
1 July 2024
Est. completion
1 May 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Incidence, severity, and type of treatment-emergent adverse events (TEAEs); Pharmacokinetics in peripheral blood; Pharmacokinetics in peripheral blood; Pharmacokinetics in bone marrow; Pharmacokinetics in bone marrow; Recommended Phase 2 Dose (RP2D) regimen finding

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov