Crohn's Disease and Colitis Trial, Recruiting NCT06494826 Sponsor: Weizmann Institute of Science Condition: Crohn's Disease and Colitis
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Crohn's Disease and Colitis Trial, Recruiting

NCT06494826
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

If you are being checked for Crohn's disease (CD):

  • You are 18 years old or older
  • You are scheduled for a colonoscopy because doctors suspect you may have newly developed Crohn's disease
  • You have not yet received any medication or special diet treatment for this condition

If you are a healthy volunteer (comparison group):

  • You are a similar age and gender to someone in the Crohn's disease group, and you are having a colonoscopy either for general digestive complaints (such as changes in bowel habits, bloating, or stomach pain) or for routine colorectal cancer screening

Who may not be able to join:

  • You have already been diagnosed with inflammatory bowel disease (such as Crohn's disease or ulcerative colitis) and have received treatment for it
  • You have a long-term digestive condition such as celiac disease or certain other chronic gut disorders
  • You have type 1 or type 2 diabetes
  • You have had cancer in the past or currently have cancer
  • Your Body Mass Index (BMI) is over 30 (confirm with trial site if unsure of your BMI)
  • You have taken antibiotics or probiotic supplements within the last 2 months
  • You have taken steroid medications (by mouth or injection) within the last 2 months — note that short-term use of steroid creams or ointments on the skin may be acceptable (confirm with trial site)
  • You have had major surgery on your stomach or intestines in the past
  • Your suspected Crohn's disease appears to affect large areas of the small intestine or colon, or you have significant problems around the anal area
  • Your condition appears to involve severe narrowing of the intestine or abnormal tunnels (fistulas) forming between organs
  • You are regularly taking any medication by mouth or injection that suppresses the immune system or reduces inflammation — however, using these as inhalers, creams, or ointments does not automatically exclude you (confirm with trial site)
  • You have a condition where your immune system does not work properly from birth
  • You are currently pregnant or have been breastfeeding in the last 6 months
  • You have a serious medical condition that the study doctors believe could affect the balance of bacteria in your gut, such as an autoimmune or rheumatic disease (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +97289524014

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Weizmann Institute of Science
Registry
ClinicalTrials.gov
Start date
1 May 2024
Est. completion
1 May 2028

Where this trial is recruiting

🇮🇱 Israel

Primary endpoints

Characterization of gut microbiota and associated molecules in Crohn's disease and healthy human gastrointestinal tract

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov