Phase 2 Oesophageal Cancer Trial, Recruiting NCT06498752 Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Condition: Oesophageal Cancer
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Phase 2 Oesophageal Cancer Trial, Recruiting

NCT06498752
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older, of any gender
  • People who have been confirmed through a tissue or cell sample to have squamous cell carcinoma (a specific type of cancer) of the esophagus (food pipe), at a stage where surgery is not possible (initial stage I–VIa)
  • People with a general health and activity level rated at 0 or 1 on a standard medical scale, meaning they are fully active or have only minor limitations in physical activity (confirm with trial site)
  • People whose routine blood tests and liver and kidney function results show no significant problems
  • People who have completed a full course of radiation therapy to the affected area, at a dose between 50 and 60 Gy
  • People who have received a specific type of chemotherapy treatment (platinum combined with paclitaxel, or a two-drug regimen based on 5-FU, with or without a PD-1 immunotherapy drug), following standard treatment guidelines — or, for older patients, a single-drug treatment called S-1
  • People who have given their written informed consent to participate

Who may not be able to join:

  • People who have had another type of cancer in the past, except for certain early-stage or non-invasive cancers such as hypopharyngeal carcinoma in situ, non-malignant skin cancer, or cervical carcinoma in situ
  • People who currently have an active infection, or who have had a serious illness such as a heart attack in the six months before enrolling
  • People who have a history of autoimmune diseases (conditions where the immune system attacks the body's own tissues)
  • People who are currently participating in another clinical trial, or who have done so within the four weeks before enrolling
  • People who have already received more than four cycles of systemic treatment (chemotherapy alone, or chemotherapy combined with immunotherapy)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

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Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Registry
ClinicalTrials.gov
Start date
16 July 2024
Est. completion
1 June 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Median progression-free survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov