Alzheimer's Disease Trial, Recruiting NCT06507254 Sponsor: University of California, Los Angeles Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT06507254
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 50 years of age or older
  • People of any gender (male or female)
  • People who have at least one parent or sibling who has been diagnosed with Alzheimer's Disease
  • People who regularly eat a typical Western-style diet — meaning a diet high in animal products, refined carbohydrates, and processed foods
  • People who are able to communicate well in English

Who may not be able to join:

  • People who follow a vegan or vegetarian diet
  • People who are already showing signs of cognitive impairment or dementia at the time of joining, as measured by specific memory and thinking tests
  • People with a pre-existing psychosis or other psychiatric condition
  • People who are currently receiving treatment for dementia
  • People with a history of alcohol or substance abuse or dependence, as determined by a structured screening interview used by the trial
  • People who smoke more than half a pack of cigarettes per day
  • People who have had a stroke or other blood vessel-related brain event in the past
  • People with an allergy to berry fruits
  • People who have taken oral or intravenous antibiotics in the last 3 months, or probiotic supplements in the last month
  • People who have changed their use of medications that affect mood, thinking, or behaviour in the last 3 months, or who take other medications that may interfere with what the trial is measuring
  • People who are experiencing frailty, malnutrition, or food allergies or intolerances that require a special diet
  • People whose body weight exceeds 400 pounds (approximately 181 kg), due to weight limits on the MRI scanning table
  • Women who are pregnant, currently breastfeeding, or who gave birth less than 6 months ago
  • Women of childbearing age who are not using birth control or who plan to become pregnant during the study period
  • People who cannot safely have an MRI scan — for example, due to claustrophobia, or because they have a pacemaker, neurostimulator, or metal objects in their body
  • People living with chronic pain

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Arpana Church, PhD, The Regents of the University of California, Los Angeles

Phone: 2670089

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
9 January 2025
Est. completion
30 June 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Differences in Polyphenol-derived metabolite concentrations pre, mid, & post intervention - stool; Differences in Polyphenol-derived metabolite concentrations pre, mid, & post intervention - blood; Differences in microbiome levels pre, mid, & post intervention - Stool; Differences in microbiome levels pre & post intervention - Blood; Differences in microbiome levels pre, mid, & post intervention - Stool; Differences in microbiome levels pre, mid, & post intervention - Blood; Differences in Cognitive Measures pre, mid, & post intervention - Executive Function; Differences in Cognitive Measures...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov