Alopecia Areata Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older
• You have been diagnosed with a condition called lichen planopilaris (LPP), a type of scarring hair loss
• You are willing to sign a consent form agreeing to take part in the study
• You do not have any known allergies or medical reasons that would prevent you from taking either of the two study medications (hydroxychloroquine or methotrexate)

Who may not be able to join:

• Your skin or scalp biopsy results show a different diagnosis than LPP
• You are unable to follow the study requirements, such as taking medications as directed, attending clinic visits, or completing questionnaires
• You have eye problems such as damage to the retina or macula (confirm with trial site)
• You have a muscle weakness condition called myasthenia gravis
• You weigh less than 35 kg (about 77 lbs)
• You are currently trying to conceive a child (this applies to both men and women), are pregnant, or are breastfeeding
• You have severe kidney or liver disease, liver scarring, or issues with alcohol use
• You have problems with your bone marrow or a weakened immune system
• You have low levels of red blood cells, white blood cells, or platelets
• You have poor nutritional status, including low protein levels in your blood
• You have a known allergy or sensitivity to the medication methotrexate
• You have had lung damage caused by methotrexate in the past, or you have significantly reduced lung function

Important: Always verify eligibility with the trial site directly before applying.