Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people with Myasthenia Gravis:

• Adults who have been diagnosed with a specific type of myasthenia gravis (anti-AChR positive autoimmune myasthenia gravis), confirmed by clinical and lab tests, and classified in a recognised severity category (Class I to IV by the MGFA)
• People who have been diagnosed with a mild or major neurocognitive disorder (a thinking or memory condition meeting DSM-5 standards) through a specialist memory centre (CMRR), including spinal fluid (CSF) testing, and who agree to allow leftover spinal fluid samples to be stored for research
• People who are willing to sign an informed consent form
• People who are enrolled in or covered by a French social security system

For people with Alzheimer's Disease:

• Adults who have been diagnosed with a mild or major neurocognitive disorder (meeting DSM-5 standards) through a specialist memory centre (CMRR), including spinal fluid (CSF) testing, and who agree to allow leftover spinal fluid samples to be stored for research
• People whose neurocognitive disorder has been linked solely to Alzheimer's disease, confirmed by recognised diagnostic criteria (IWG-2) and Alzheimer's-specific markers found in spinal fluid
• People who are willing to sign an informed consent form
• People who are enrolled in or covered by a French social security system

For healthy volunteers (control group):

• People who have no memory complaints
• People who have no neurocognitive disorder
• People who have previously agreed to have their spinal fluid samples, stored at a biobank at the Institute of Translational Neurology in Münster, Germany, used for research analysis

Who may not be able to join:

For people with Myasthenia Gravis:

• People who do not have sufficient command of the French language to understand, read, and complete neuropsychological tests
• People whose routine spinal fluid sample is needed for other standard diagnostic tests as part of their regular medical care
• People who fall into certain protected or vulnerable categories, including: pregnant women, women who have recently given birth, or breastfeeding mothers; people deprived of their liberty by a judicial or administrative decision; people hospitalised without their consent under specific French legal provisions; people admitted to a health or social facility for reasons other than research; and adults under a legal protection measure or who are unable to give their own consent

For people with Alzheimer's Disease:

• People who fall into certain protected or vulnerable categories, including: pregnant women, women who have recently given birth, or breastfeeding mothers; people deprived of their liberty by a judicial or administrative decision; people hospitalised without their consent under specific French legal provisions; people admitted to a health or social facility for reasons other than research; and adults under a legal protection measure or who are unable to give their own consent

Important: Always verify eligibility with the trial site directly before applying.