Phase 2 Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• In Part 1 of the trial, you must be between 18 and 90 years old; in Part 2, you must be between 13 and 90 years old
• You have been diagnosed with leukemia or lymphoma that has come back after treatment or has not responded to treatment, as defined by the trial's specific guidelines
• Your cancer cells must test positive for a protein called CD19
• You must have a low enough level of antibodies to a specific virus used in the treatment (called AAV) in your blood (confirm with trial site)
• Your kidneys, liver, heart, and lungs must be functioning within the ranges required by the trial
• Your blood cell counts and related measurements must fall within the ranges required by the trial

Who may not be able to join:

• You have signs of liver stress, shown by elevated levels of certain liver enzymes in your blood (confirm with trial site)
• You have a history of a blood vessel disorder called thrombotic microangiopathy, a heart muscle disease called cardiomyopathy, or you currently have problems with nerve sensitivity or sensation
• You are currently pregnant or breastfeeding
• You have moderate to severe acute Graft versus Host Disease (a complication sometimes seen after transplants), or any level of chronic Graft versus Host Disease
• You have a history of being allergic to steroid medications, or have had serious side effects from them in the past
• You have received chemotherapy too recently before joining the trial, within timeframes set out by the trial guidelines

Important: Always verify eligibility with the trial site directly before applying.