Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with intermediate-risk prostate cancer, based on national guidelines
• Your PSA blood test result is between 10 and 20 ng/ml, OR your Gleason score (a measure of cancer aggressiveness) is 7, OR your cancer has spread within the prostate to more than half of one side or to both sides
• You are older than 18 years of age
• You are in good general health, able to carry out normal daily activities with only minor difficulty (confirm with trial site)
• Your prostate is smaller than 90 cc (a measure of prostate size)
• An MRI scan has identified a visible area of concern in your prostate of at least 0.5 cm, with no more than two other areas of concern, rated as high suspicion on a standard scoring system
• Your MRI scan shows the cancer may be touching the outer edge of the prostate, but has not clearly spread beyond it
• Your urinary symptom score is below 18 on a standard questionnaire, meaning your symptoms are mild to moderate
• You are willing and able to complete an MRI safety screening form and meet MRI safety requirements

Who may not be able to join:

• Your Gleason score is higher than 7
• Your PSA blood test result is above 20 ng/ml
• You are currently receiving or have previously received hormone therapy to lower testosterone for prostate cancer
• Your MRI scan strongly suggests the cancer has spread outside the prostate
• Your MRI scan shows more than two areas of disease in the prostate
• There is evidence that your cancer has spread to your bones or other parts of your body
• You cannot have an MRI scan due to a pacemaker, defibrillator, other implanted metal or electronic device, severe fear of enclosed spaces, or inability to lie still for the required time
• You have a metal implant or device in your pelvis area that could affect MRI image quality
• Your body measurements are too large to be compatible with the specific MRI technology used in this trial (confirm with trial site)
• You have an allergy or medical reason preventing you from receiving gadolinium, a dye used during MRI scans
• You have had a previous procedure to remove prostate tissue through the urethra (TURP)
• You have a history of urethral stricture (narrowing of the tube that carries urine)
• You have previously had radiation treatment to your pelvic area
• You have a history of inflammatory bowel disease
• Your MRI or CT scan shows the cancer has spread significantly beyond the prostate or to nearby lymph nodes
• You are unable to give informed consent to participate
• You are unable to complete quality of life questionnaires
• Your blood test results show abnormalities, including low platelet count, low haemoglobin (anaemia), low white blood cell count, or poor kidney function

Important: Always verify eligibility with the trial site directly before applying.