Phase 1 Oesophageal Cancer Trial, Recruiting NCT06545331 Sponsor: Exelixis Condition: Oesophageal Cancer
Back to Oesophageal Cancer

Phase 1 Oesophageal Cancer Trial, Recruiting

NCT06545331
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older at the time you sign the consent form
  • You must be fairly active and able to carry out daily activities with little or no limitations (this is measured by a standard scale doctors use called ECOG, scored 0-1)
  • Your liver, kidneys, bone marrow, and other organs must be working well enough to safely participate (confirm with trial site for specific lab requirements)
  • You must have a solid tumour that has been confirmed by biopsy or tissue sample and imaging scans, and the tumour cannot be removed by surgery, or has spread, come back, or is in an advanced stage
  • In a later stage of the trial, participants must have one of these specific cancer types: non-small cell lung cancer, hormone-receptor-positive breast cancer, head and neck cancer, esophageal squamous cell cancer, or triple-negative breast cancer
  • You must be able to understand and follow the study requirements, and must sign a consent form agreeing to participate

Who may not be able to join:

  • No exclusion criteria were listed in the information provided (confirm all eligibility details with the trial site directly)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Study Director, Exelixis

Phone: 1-888-EXELIXIS (888-393-5494)

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Exelixis
Registry
ClinicalTrials.gov
Start date
6 August 2024
Est. completion
23 November 2026

Where this trial is recruiting

🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Dose-Escalation Stage: Maximum tolerated dose (MTD) and/or Recommended dose(s) for Expansion [RDE(s)] for XB010; Dose-Escalation Stage: Safety of XB010; Dose-Escalation Stage: Duration of exposure of XB010 [Tolerability]; Dose-Escalation Stage: Dose intensity of XB010 [Tolerability]; Cohort-Expansion Stage: Preliminary antitumor activity of XB010

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov