Ovarian Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Female participants between 18 and 75 years of age (including those exact ages)
• People who have an ovarian or pelvic mass that has not yet been treated, which may be on one or both sides, and may be a single or multiple fluid-filled or solid growth
• People expected to live for at least 3 months
• People with a malignant (cancerous) tumor who are still able to carry out basic daily activities with little or no limitation (as measured by a standard medical scale called ECOG, scoring 0 to 2)
• People whose blood cell counts, liver, kidney, clotting, electrolyte, and heart function results meet the specific healthy ranges required by the trial (confirm with trial site for exact values)
• People who are able to use an effective form of contraception throughout the trial, such as sterilisation, an IUD, condoms, contraceptive pills, abstinence, or a partner who has had a vasectomy
• People who understand what the trial involves, are willing to take part, and are able to sign a consent form agreeing to follow the trial requirements

Who may not be able to join:

• People whose mass has been confirmed as a benign (non-cancerous) teratoma
• People who have had both ovaries and fallopian tubes completely removed
• People born with structural abnormalities of the reproductive system
• People who have received radiotherapy, chemotherapy, or invasive procedures such as radiofrequency ablation during the period when the trial treatment and diagnostic assessments are taking place
• People who are currently pregnant, breastfeeding, planning to become pregnant within 6 months, or who have a positive pregnancy test at the time of screening
• People with a known allergy to any component of the trial drug (FRD001 injection), or a history of other serious allergic reactions
• People whose ultrasound results show that a clear enough image of the area cannot be obtained (known as an insufficient acoustic window)
• People who have medical reasons that prevent them from having the imaging tests required by the trial (confirm with trial site)
• People with serious lung conditions such as acute respiratory distress syndrome, severe emphysema, pulmonary vasculitis, or pulmonary embolism
• People with serious heart or stroke-related conditions, including significant abnormal heart rhythms, recent heart attack, heart failure, stroke, or aortic problems within the past 6 months, or a heart pumping function below 50%
• People with severely high blood pressure that is not controlled, or known severe high blood pressure in the lungs (confirm with trial site for specific blood pressure thresholds based on age)
• People with brain metastases (cancer that has spread to the brain) that are causing symptoms and require treatment
• People with a severe or uncontrolled mental health condition
• People with an active infection requiring treatment, or an uncontrolled infection within 14 days before starting the trial drug
• People who test positive for HIV, hepatitis C, syphilis, or hepatitis B surface antigen
• People with a history of abnormal connections between the right and left sides of the heart (cardiac shunts)
• People with a history of alcohol or drug abuse or dependence
• People who have taken part in another clinical trial involving an experimental drug within the 30 days before screening
• People taking medications or receiving treatments that the trial doctor believes could interfere with the trial results or cause serious side effects, and which have not been fully cleared from the body before enrolment
• People whom the trial doctor considers unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.