Alzheimer's Disease Trial, Recruiting NCT06566170 Sponsor: Eli Lilly and Company Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT06566170
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are receiving care for what their doctor suspects is mild cognitive impairment (MCI) or early-stage Alzheimer's disease (a formal diagnosis confirmed by lab tests or medical records is not required before screening)
  • People who score 21 or higher on a phone-based memory and thinking test called the TICS
  • People who have test results (such as a brain scan or spinal fluid or blood test) showing the presence of a protein called amyloid beta in the brain, which is linked to Alzheimer's disease (results from within the past 12 months may be accepted)
  • People who have a trusted person in their life — such as a family member or close friend — who is in regular contact with them and is able to take part in phone check-ins every 6 months
  • People who have electronic health records (digital medical records) available and are willing to allow the trial team to access those records for the duration of the study

Who may not be able to join:

  • People who have had a stroke in the past and, as a result, are unable to independently perform at least one basic daily activity such as walking, eating, bathing, dressing, or using the toilet (note: people with a mix of dementia types that also involve amyloid protein may still be considered)
  • People who currently have, or have recently had, a serious or unstable health condition (other than Alzheimer's disease) that the trial doctor believes could make it difficult to complete the study — for example, a life expectancy of less than 36 months, a need for long-term residential care, or a serious mental health condition
  • People who are already enrolled in, or are planning to join, another clinical trial testing an investigational treatment
  • People who have medical reasons they cannot receive the drug donanemab, cannot have an MRI scan, or cannot have an amyloid brain scan — this applies only to participants in the donanemab group of the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST), Eli Lilly and Company

Phone: 1-317-615-4559

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
7 October 2024
Est. completion
1 February 2033

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Time to First Increase in Dependence Level Above Baseline (as derived from the Dependence Scale [DS])

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov