Phase 2 Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who understand what the study involves and are willing to sign a consent form
• People aged 18 or older, of any gender
• People newly diagnosed with a specific type of lymphoma called DLBCL (confirmed by tissue testing), who have not yet received treatment, and who have at least one tumour that can be measured using standard imaging methods
• People with a low-to-moderate disease risk score (IPI score of 0–2) (confirm with trial site)
• People who are reasonably active and able to carry out daily activities, based on a standard performance scale (ECOG score of 0–2) (confirm with trial site)
• People who have not received certain blood-boosting medications or blood transfusions within one week before a screening blood test
• People whose doctors estimate they will survive for more than 3 months
• People whose organs (such as liver, kidneys, and heart) are functioning well enough to meet the trial's requirements (confirm with trial site)
• People who are willing and able to attend all scheduled visits and follow the study plan
• Women who could become pregnant must have a negative pregnancy blood test within 3 days before starting the trial, and both male and female participants who could father or become pregnant must agree to use highly effective contraception during the study and for 3 months after the last dose

Who may not be able to join:

• People currently taking part in another clinical trial involving a treatment intervention
• People who have had, or currently have, another type of cancer
• People whose lymphoma has spread into the bone marrow
• People who have brain involvement from their lymphoma that requires immediate treatment with radiation or steroids
• People with a known allergy to any of the drugs or ingredients used in the trial
• People who have previously had a stem cell or bone marrow transplant
• People with an active infection that requires systemic (whole-body) treatment
• People with serious heart problems that are not under control
• People who have a severe active infection or an unexplained fever above 38.5°C at the time of screening or before the first dose (though the trial site may allow enrolment if the fever is judged to be caused by the tumour itself)
• People who have had radiation therapy anywhere on their body within 2 weeks before starting the study
• People who have taken any experimental drug within 4 weeks before starting the study
• People who have received a live vaccine (such as certain flu or travel vaccines) within 4 weeks before starting the study, or who may need one during the study (standard seasonal flu vaccines may still be allowed during flu season)
• Women who are pregnant or breastfeeding
• People whom the treating doctor believes should not participate, for any other reason

Important: Always verify eligibility with the trial site directly before applying.