Crohn's Disease and Colitis Trial, Not Yet Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Phase A (active disease group):

• You are 18 years old or older
• You have been diagnosed with ulcerative colitis (UC) for at least 3 months
• Your UC is currently moderately to severely active, based on a standard scoring system
• Your doctor has recommended starting a targeted treatment for your UC, but you have not begun it yet
• If you are taking steroid tablets (like prednisone), your dose has been stable for at least 3 weeks and is no higher than 20 mg per day
• You are scheduled for a colonoscopy to check your disease activity as part of your normal care
• You are able to follow all the study procedures
• Your Body Mass Index (BMI) is below 23

Phase B (remission group):

• You are 18 years old or older
• You have been diagnosed with UC and your disease is currently in remission (well controlled) while on a targeted therapy
• You are able to follow all the study procedures
• Your BMI is below 23

Who may not be able to join:

• You have been diagnosed with a different type of colitis, such as Crohn's, microscopic, ischemic, infectious, or radiation-related colitis
• You have a medical reason why a colonoscopy would not be safe for you, or you had serious complications during a previous colonoscopy
• You have a bleeding disorder
• You need surgery for your UC
• You do not have the legal capacity to give consent for yourself
• You have used rectal treatments (enemas or suppositories) within the 2 weeks before the study starts
• You have been taking more than 20 mg of prednisone within the 3 weeks before the study starts
• You have low levels of haemoglobin (a measure of anaemia) at the start of the study
• You are pregnant or breastfeeding
• You have an implanted contraceptive device (such as a coil/IUD)
• Your BMI is above 23
• You have been diagnosed with cancer, especially bowel or rectal cancer
• You have a type of osteoporosis involving very rapid bone loss (confirm with trial site)
• You have metal fragments in your body
• You have joint replacements (prostheses)
• You have varicose veins
• You have a condition involving inflamed veins (phlebitis or thrombophlebitis)
• You have a pacemaker fitted
• You have a serious condition affecting blood flow in the arteries (obliterating arteriopathy) (confirm with trial site)
• You are currently menstruating at the time of the study procedure
• You have cancerous tissue or are near an area being treated for cancer
• You have tuberculosis
• You are a child or adolescent still in a growth phase
• You are unable to communicate or describe feelings of pain
• The study doctor considers you unsuitable to participate for any other reason

Important: Always verify eligibility with the trial site directly before applying.