Motor Neurone Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
If you have ALS:
- You are 18 years of age or older
- You are able to understand and agree to take part in the study on your own
- You are willing to follow the study's procedures
- A doctor has diagnosed you with ALS
- You have access to a smartphone, tablet, or computer with internet (this can be at a public library or another location — it does not need to be at home)
If you do not have ALS (control participant):
- You are 18 years of age or older
- You are able to understand and agree to take part in the study on your own
- You are willing to follow the study's procedures
- You have never been diagnosed with ALS, Progressive Muscular Atrophy (PMA), or Primary Lateral Sclerosis (PLS)
- You do not have a close family history of inherited ALS or a related condition called Frontotemporal Dementia (FTD), unless you have previously been tested and shown not to carry the relevant genetic change (confirm with trial site)
- You have access to a smartphone, tablet, or computer with internet (this can be at a public library or another location — it does not need to be at home)
Who may not be able to join:
- People with serious cognitive difficulties, dementia, or unstable mental health conditions — such as psychosis, active thoughts of suicide, a recent suicide attempt, or untreated severe depression within the past 90 days — that could interfere with taking part, as judged by the study doctor
- People with a serious, unstable medical condition (other than ALS) — such as heart instability, an active widespread infection, untreated thyroid problems, or a progressive cancer — that might make it unlikely they could complete 12 months of follow-up, as judged by the study doctor
Additional reasons someone may not be able to take part in the optional spinal fluid sample procedure (lumbar puncture):
- People who are medically unable to have a lumbar puncture (spinal tap) — for example, due to a bleeding disorder, a skin infection near the procedure site, or raised pressure in the brain or spine (confirm with trial site)
- People who are allergic to Lidocaine or similar local anaesthetic medicines
- People taking blood-thinning or anti-clotting medications (other than low-dose aspirin 81mg) that cannot safely be stopped before the procedure
- People with a blood or bleeding disorder, or who are on kidney dialysis
- People who are currently pregnant (based on self-report)
- People who the study doctor feels would be unable to undergo the procedure more than once
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 602-845-0248
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
ALS Functional Rating Scale-Revised (ALSFRS-R); ALS Functional Rating Scale-Revised Self entry (ALSFRS-RSE)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.