Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have had one ischemic or hemorrhagic stroke (confirmed by brain imaging) between 3 and 9 months before joining the trial
- People whose arm movement on the affected side falls within a specific range on a standard motor scoring test (Fugl-Meyer arm score between 19 and 55), indicating partial weakness (confirm with trial site)
- People whose leg movement on the affected side scores below 34 on the same standard motor scoring test, showing some remaining weakness on one side of the body (confirm with trial site)
- People who are able to walk at least 20 meters with no more than a light steadying hand from another person
- People between 18 and 85 years of age
Who may not be able to join:
- People who have been hospitalised for a heart attack, heart failure, or heart surgery within the past 3 months
- People who have an irregular heart rhythm (cardiac arrhythmia)
- People who have a condition where the heart muscle is abnormally thick (hypertrophic cardiomyopathy)
- People who have had more than one stroke
- People who are currently receiving physical or occupational therapy, or who are already enrolled in another interventional research study
- People who have severe narrowing of the main heart valve (severe aortic stenosis)
- People who have an untreated blood clot in a vein or in the lungs
- People who have unstable chest pain (unstable angina)
- People whose blood pressure is not well controlled
- People who have an implanted pacemaker or defibrillator
- People who experience shortness of breath while at rest
- People who have a significant neurological condition or diagnosis other than stroke
- People with a recent history of illicit drug or alcohol misuse, or a significant mental health condition
- People who have significant joint stiffness or tightening of muscles (contractures)
- People who have received an anti-spasticity injection (such as Botox) within 3 months before joining the trial
- People who have metal hardware in their skull (such as screws or plates) or who have had previous brain surgery, which could interfere with brain activity measurements
- People who have any other medical reason that prevents them from safely exercising or undergoing brain activity monitoring (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Susan Linder, PT, DPT, PhD, The Cleveland Clinic
Phone: 216 509-7012
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Upper Extremity Fugl-Meyer Motor Assessment; Gait Velocity; Plasma IGF-1; Serum BDNF; electroencephalograms; electroencephalograms; electroencephalograms; Incremental cost-effectiveness ratio; Stroke Impact Scale
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.