Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults under 70 years of age who were previously physically active and have knee osteoarthritis that significantly limits daily life
- People whose knee osteoarthritis has not responded to standard treatments such as anti-inflammatory medications, injections, or pain relief medications
- People who have a knee alignment problem (deformity) of less than 10 degrees, and this would be their first implant in that knee
- People who have given written agreement to take part in the trial
- People who are registered with the French social security system
Who may not be able to join:
- People with a knee deformity greater than 10 degrees
- People with a BMI (body mass index) over 30, which is classified as obesity
- People with an inflammatory joint disease, such as rheumatoid arthritis
- People with a history of joint infection
- People with poor skin condition around the knee area
- People with a known allergy to the materials used in the implant or to the anaesthetic used during surgery
- People who have repeated falls, or significant neurological, mental, or neuromuscular conditions that could lead to complications after surgery
- People with significant weakness or damage to the stabilising ligaments on the sides of the knee
- Women who are pregnant, within 48 hours of giving birth, breastfeeding, or who test positive on a pregnancy test
- People who have a strong fear of MRI scans and refuse to have one
- People who cannot have an MRI scan for medical reasons, such as having an active implanted medical device or certain metal implants in the body
- People who are under a legal protection order (confirm with trial site)
- People who are currently taking part in another clinical trial
- People whose osteoarthritis developed as a result of a previous bone fracture
- People who have osteoporosis (weakened or brittle bones)
- People whose bone shape or size is not compatible with the implant being used in this trial
- People with another serious health condition that would prevent them from returning to physical activity after surgery
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Pascal BIZOT, MD, Pr, APHP
Phone: +33 (0)1 49 95 91 34
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Evaluation of clinical endpoint 1(Oxford score) at 12 months; Evaluation of clinical endpoint 2 (IKS score) at 12 months; Evaluation of clinical endpoint 3 (Forgotten Joint score) at 12 months; Evaluation of clinical endpoint 4 (Joint sounds) at 12 months; Evaluation of clinical endpoint 5 (Pain) at 12 months; Evaluation of clinical endpoint 6 (Knee mobility) at 12 months; Evaluation of clinical endpoint 7 (Knee stability) at 12 months; Evaluation of radiographic endpoints at 12 months
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.