Phase 2 Crohn's Disease and Colitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with ulcerative colitis (UC) for at least 3 months before the start of the trial.
• People whose UC is considered moderately to severely active, based on a standard UC disease activity score.
• People whose UC has not responded well to, has stopped responding to, or who could not tolerate at least one standard medication (such as corticosteroids) or one advanced treatment (such as biologics, JAK inhibitors, or S1P immunomodulators).
• People who are currently taking certain oral UC medications, including corticosteroids, at a stable dose.
• People who meet the trial's specific contraception requirements (confirm with trial site for details).

Who may not be able to join:

• People who have previously received certain types of antibody treatments targeting specific proteins involved in inflammation (anti-IL-23p19 or anti-IL-12p40 antibodies).
• People who have had a blood clot or similar event within 24 weeks before the start of the trial.
• People who currently have a diagnosis of Crohn's Disease or certain other inflammatory conditions affecting the digestive tract.
• People who have had certain abdominal surgeries in the past 3 months, or who are likely to need surgery for their UC during the trial period.
• People who have a history of certain types of pre-cancerous growths or cancers (confirm with trial site for specific details).

Important: Always verify eligibility with the trial site directly before applying.