Phase 3 Crohn's Disease and Colitis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older (any gender) with a confirmed diagnosis of ulcerative colitis (Group 1), OR males aged 30 or older and females aged 40 or older with a confirmed diagnosis of ulcerative colitis (Group 2)
- People whose disease is currently active, as confirmed by a camera examination of the bowel (with a score of 2 or higher on a standard medical scale)
- People for whom a doctor has determined that treatment with a medication called filgotinib is appropriate
- People whose active disease is also confirmed by a bowel ultrasound scan showing thickening in at least one bowel area plus at least one other abnormal finding, OR people who have elevated levels of certain inflammation markers in their blood (CRP above 5 mg/L) and/or stool (calprotectin above 250 mg/kg)
Who may not be able to join:
- People who are currently pregnant
- People who are not able to give their own informed consent to participate in the trial
- People who have colorectal cancer or a serious type of pre-cancerous cell change in the bowel called high-grade dysplasia
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Mark Lowenberg, MD PhD, Amsterdam UMC, location VUmc
Phone: +31205668160
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Candidate fibrotic cellular pathways
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.