Pulmonary Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are between 18 and 70 years old (male or female)
- Your right atrial pressure (a measurement of pressure in the right side of your heart) falls within a specific range, between 10 and 20 mmHg (confirm with trial site)
- You have been diagnosed with severe idiopathic pulmonary hypertension, meaning high blood pressure in the lungs with no known cause, and your average lung artery pressure is above 45 mmHg
- Your condition is classified as WHO grade III or IV, meaning your symptoms significantly limit your daily activities
- Your blood test shows a specific heart stress marker (NT-proBNP) at 650 ng/L or higher
- You are willing to sign a consent form, attend follow-up appointments, and complete any required tests during the study
Who may not be able to join:
- You currently have a local or widespread infection, such as sepsis
- You have a serious blood clotting disorder
- You have a known allergy to nickel, titanium, or materials made from these metals
- You cannot take blood-thinning or anti-clotting medications for medical reasons
- You have had a reaction to contrast dye (the liquid sometimes used in scans)
- You are currently taking part in another clinical trial for a drug or medical device
- Your kidneys are not filtering blood well enough (kidney filtration rate below 50 mL/min)
- You have severe liver problems, shown by certain liver enzyme levels being more than 3 times higher than normal
- You have a serious heart rhythm problem
- You have not been receiving the standard recommended medication treatment for pulmonary hypertension (a three-drug treatment plan) for at least the past 3 months
- You are pregnant, breastfeeding, or planning to become pregnant within the next 12 months
- You have severe lung disease that significantly limits airflow or lung expansion
- You already have a device implanted to close a hole in the wall between the upper chambers of your heart
- Your heart's pumping function is below a certain level (left heart pumping efficiency below 50%)
- Your blood oxygen level, measured without extra oxygen, is below 90%
- The structure of your heart makes it impossible to place the study device in the wall between the upper chambers
- The trial doctor has another reason to consider you unsuitable for the trial (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Junbo GE, Prof., Fudan University
Phone: 13801641252
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
All-cause mortality at 6 months; Rehospitalization rates associated with exacerbation of pulmonary arterial hypertension
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.