Phase 2 Peripheral Arterial Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You were first diagnosed between the ages of 18 months and 18 years, and you are at least 3 years old at the time of joining the trial.
• You have a solid tumour that has come back or stopped responding to treatment, and a recent scan (done within the last 3 months) showed that your tumour has enough of a specific protein called somatostatin receptors on its surface (a score of 2 or higher on the scan).
• You are generally well enough to carry out some daily activities, as measured by a standard health scale used for children and young people.
• Your doctors expect you to live for at least 3 more months.
• You are able to swallow tablets or capsules.
• Your blood counts, kidney function, liver function, and protein levels are within acceptable ranges based on tests done in the last 28 days (confirm specific values with trial site).
• If you are female and have started your periods, or are 12 years old or older, a pregnancy test must come back negative before joining.
• If you could become pregnant or father a child, you must agree to use reliable contraception during the trial and for several months after the last dose of the study treatments.
• You (and your parent or guardian if you are under 18) are willing and able to give written consent to take part in the trial.
• You have recovered well enough from any major surgery before starting the study treatment.
• There are no significant personal, family, social, or location-related reasons that would make it hard for you to follow the trial schedule and attend appointments.

Who may not be able to join:

• You have previously had a serious liver reaction caused by a medication that required dose changes or stopping treatment, or that the doctor feels could pose a risk.
• You have already received more than one treatment with a type of radioactive drug similar to the one used in this trial (radiolabelled somatostatin analogues).
• You are unable to swallow tablets or capsules.
• You are currently receiving any other cancer treatments or experimental treatments, or it has been less than 28 days since your last cancer treatment (or less than 4 months if that treatment was a type of immunotherapy called a checkpoint inhibitor).
• You have received a specific type of long-acting hormone-blocking drug (long-acting somatostatin analogue) within the last 28 days.
• You have a known allergy to any of the ingredients in the study medications (confirm with trial site).
• You currently have an infection that is not under control.
• You are currently breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.