Phase 2 Prostate Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have given written agreement to take part in the trial.
- You are male and aged 18 or older.
- You have been diagnosed with prostate cancer (a specific type called adenocarcinoma) confirmed by a tissue test.
- Your prostate cancer has stopped responding to hormone-lowering treatments, and your testosterone levels are very low (below 50 ng/dL).
- Your cancer has spread to other parts of the body (metastatic).
- You are currently receiving treatment to lower testosterone (via injections or implants), or you have had both testicles surgically removed.
- You have previously received at least one course of chemotherapy (taxane-based) and at least one hormonal treatment (such as abiraterone or enzalutamide) — or you were unable to tolerate or refused chemotherapy.
- You are generally well enough to carry out daily activities with little or no limitation (confirm with trial site).
- Your bone marrow, liver, and kidneys are working well enough based on blood tests.
- Your blood clotting level is within an acceptable range (confirm with trial site).
- You are able to swallow the study medication.
- Your doctors expect you to live for more than 3 months.
Who may not be able to join:
- You have a bowel condition such as Crohn's disease, or have had major surgery on your digestive system that could affect how your body absorbs medication.
- You have a history of problems with your pituitary gland or adrenal glands.
- You have diabetes that is not well controlled.
- You have significantly abnormal potassium or sodium levels in your blood.
- You have a serious non-cancer illness (such as kidney blockage or liver failure) that could interfere with the trial, in the opinion of the medical team.
- You have an active or unstable heart or stroke-related condition, including blood clots.
- You have a history of heart failure, significant heart disease, or a heart attack within the last 6 months.
- You have an abnormal heart rhythm reading on an ECG (a specific measurement called QTcF) (confirm with trial site).
- You have an active infection or another condition that would make taking steroid medication unsafe.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 1 908 240 7514
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Phase 1: Maximum tolerated dose (MTD); Phase 1: Recommended dose range (RDR); Phase 2: Evaluate Radiographic progression-free survival (rPFS); Phase 2: Evaluate overall response rate (ORR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.