Phase 3 Prostate Cancer Trial, Recruiting NCT06625034 Sponsor: Mayo Clinic Condition: Prostate Cancer
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Phase 3 Prostate Cancer Trial, Recruiting

NCT06625034
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older
  • People who have been diagnosed with prostate cancer confirmed by a tissue sample (biopsy)
  • People whose cancer falls within certain stages of spread, as classified by a standard medical staging system (confirm with trial site if unsure about stage)
  • People who are planned to receive a full course of radiation therapy directed at the prostate or the area where the prostate was removed
  • People who have a general health and activity level rated at a certain level (ECOG 0–2), meaning they are fully active to capable of some self-care, assessed within 90 days of joining the trial
  • People who are able to sign a consent form approved by the trial's ethics board
  • People who are able to complete all required tests before joining, within set timeframes
  • People who are able to begin radiation treatment within 180 days of registering for the study

Who may not be able to join:

  • People who have previously had radiation to the pelvic area at a dose greater than 5 Gy
  • People for whom radiation to the pelvic lymph nodes is planned as part of their treatment
  • People for whom internal radiation therapy (brachytherapy) to the prostate is planned
  • People who currently have active rectal diverticulitis, Crohn's disease affecting the rectum, or active ulcerative colitis
  • People who have previously had a hip replacement or a penile implant
  • People with a significant medical, addiction-related, or mental health condition that, in the treating doctor's opinion, would affect their ability to consent, complete treatment, or attend follow-up appointments
  • People who use a urinary catheter, either permanently or on and off

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Nathan Y. Yu, MD, Mayo Clinic

Phone: 855-776-0015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
2 February 2025
Est. completion
28 May 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of grade 3 or higher genitourinary (GU) and gastrointestinal (GI) adverse events (AEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov