Peripheral Arterial Disease Trial, Recruiting NCT06626646 Sponsor: Canadian Medical and Surgical Knowledge Translation Research Group Condition: Peripheral Arterial Disease
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Peripheral Arterial Disease Trial, Recruiting

NCT06626646
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 to 80 years old who have been diagnosed with peripheral artery disease (PAD) — a condition causing leg pain during walking — with a specific test result confirming reduced blood flow to the legs.
  • Adults aged 18 to 80 years old who have never been diagnosed with peripheral artery disease (PAD).
  • People who are willing and able to sign a consent form and follow the study procedures.

Who may not be able to join:

  • People who are unable or unwilling to sign a consent form or provide a blood sample.
  • People with a serious illness that doctors expect may result in death within two years.
  • People with an active cancer diagnosis that is not considered cured (basal cell skin cancer is an exception). Cancer is generally considered cured if there has been no sign of it returning in the past five years.
  • People with high blood pressure that is not well controlled by treatment.
  • People with a very severe form of heart failure, classified as New York Heart Association Class IV (confirm with trial site).
  • People with active liver disease or poor liver function.
  • People with active kidney disease or poor kidney function.
  • People with a history of bleeding stroke or another major bleeding condition.
  • People with a white blood cell count at or above a certain high level detected in a blood test (confirm with trial site).
  • People with an active infection currently being treated with antibiotic or antiviral medicines.
  • People with HIV/AIDS.
  • People currently taking oral steroid medicines (such as prednisone) or other medicines that suppress the immune system (such as methotrexate).
  • People who have an autoimmune disorder that has been or is being treated.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Subodh Verma, MD, University of Toronto

Phone: 604-703-5449

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Canadian Medical and Surgical Knowledge Translation Research Group
Registry
ClinicalTrials.gov
Start date
1 October 2024
Est. completion
1 July 2025

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

The difference in the frequency / absolute number of circulating primitive myeloid progenitor cells (ALDHhiSSClow) between individuals with PAD and without PAD

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov