Early Phase 1 Stroke Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people without a history of stroke (neurotypical participants):

• People who are 18 years old or older
• People who have no history of stroke
• People who are able to give their own informed consent to participate

For people who have had a stroke (stroke participants):

• People who are 18 years old or older
• People who had their stroke at least 8 months ago
• People who have available medical records and brain scan information showing where the stroke occurred
• People who have weakness or reduced movement on one side of the body
• People whose stroke affected the primary motor area of the brain
• People who have some ability to move both the shoulder and elbow on the affected side

Who may not be able to join:

For people without a history of stroke (neurotypical participants):

• People with serious medical conditions, including heart, bone and joint, or neurological problems
• People with medical conditions that affect movement, range of motion, strength, or coordination of the arms and hands
• People with vision problems that would affect their ability to complete the experiment — vision and depth perception will be tested using standardised assessments (confirm with trial site for exact cut-off scores)
• People with blood pressure above 140 (top number) and/or 90 (bottom number)
• People with a blood oxygen level below 92% as measured by a finger pulse reader

For people who have had a stroke (stroke participants):

• People who have weakness or reduced movement on both sides of the body
• People with communication difficulties, cognitive impairment, or emotional or behavioural changes that would affect their ability to take part — this will be assessed using a standardised memory and thinking test, with cut-off scores that vary depending on education level (confirm with trial site)
• People with vision problems or difficulty noticing things on one side of their visual field that would prevent them from seeing targets during the experiment — this will be assessed using standardised vision and attention tests (confirm with trial site for exact cut-off scores)
• People with a muscle stiffness score of 4 at the shoulder or elbow on a standard clinical scale
• People who score below 15 on a standard arm movement assessment scale
• People who are unable to give their own informed consent
• People with serious current medical problems
• People with severe loss of sensation in the affected arm
• People whose stroke caused damage in multiple or widespread areas of the brain, or who have had more than one stroke
• People who are unable to get into or hold the positions required for testing
• People who have received Botox or similar injections in the affected arm within the past 4 months
• People who are currently taking part in any other arm rehabilitation programme, whether as part of a research study or as a prescribed therapy
• People with other neurological, neuromuscular, or bone and joint conditions affecting the arm or hand
• People with other neurological conditions such as Parkinson's disease or cerebral palsy
• People with blood pressure above 140 (top number) and/or 90 (bottom number)
• People with a blood oxygen level below 92% as measured by a finger pulse reader

Important: Always verify eligibility with the trial site directly before applying.