Ankylosing Spondylitis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
If you have axial spondyloarthritis (axSpA):
- You have been diagnosed with axSpA by a specialist rheumatology doctor
- You are 18 years old or older
- You do not have other significant heart or blood vessel conditions
- You are currently on a stable dose of biologic medication (a type of specialist treatment)
- You are able to commit to the time required by the study
If you are a healthy volunteer (comparison group):
- You are between 18 and 65 years old
- You are not taking any long-term medication that affects your immune system or inflammation
- You are currently free from any infection or infection symptoms
Who may not be able to join:
If you have axSpA:
- You are unable to exercise due to physical or mental health barriers
- You have a condition affecting your hip or other joints beyond your spine
- You have a medical reason that means exercise training is not safe for you (confirm with trial site)
- You are already very highly physically active (based on a standard physical activity questionnaire)
- You are unable to communicate sufficiently in English
- You are pregnant, breastfeeding, or planning to become pregnant during the study (applies to female participants)
- You are unable to give informed consent or follow the study procedures for any reason
- You have chronic anaemia (low red blood cell levels — confirm with trial site for specific values)
- You have another health condition that the research team considers unsafe for participation
If you are a healthy volunteer:
- You are unable to exercise due to physical or mental health barriers
- You are already very highly physically active (based on a standard physical activity questionnaire)
- You are unable to communicate sufficiently in English
- You are pregnant, breastfeeding, or planning to become pregnant during the study (applies to female participants)
- You are unable to give informed consent or follow the study procedures for any reason
- You have been diagnosed with an immune system disorder
- You have a heart, blood vessel, or metabolic condition, such as high blood pressure, high cholesterol, or diabetes
- You have any long-term health condition that affects your ability to take part in physical activity
- You have a muscle or joint injury that affects your ability to take part in physical activity
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Arumugam Moorthy, Dr, University Hospitals, Leicester
Phone: 01509226385
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Changes in spinal pain before (week 0 - baseline), and during (weeks 4, 8, and 12), the 12-week home based exercise intervention.; Changes in inflammatory monocyte phenotypes before (week 0 - baseline), and during (weeks 4, 8, and 12), the 12-week home based exercise intervention; Changes in ankylosing spondylitis disease activity before (week 0 - baseline), and during (weeks 4, 8, and 12), the 12-week home based exercise intervention.; Changes in characteristics of T-cell cell phenotypes (senescence) before (week 0 - baseline), and during (weeks 4, 8, and 12), the 12-week home based exercise...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.