Alzheimer's Disease Trial, Recruiting NCT06678100 Sponsor: Vanderbilt University Medical Center Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT06678100
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

This trial has three different groups of participants. Here is who may qualify for each:

Group 1 – People with Alzheimer's Disease (AD):

  • You are 60 years old or older
  • You have been diagnosed with Alzheimer's disease by a neurologist, confirmed through brain scans, a spinal tap, and thinking/memory tests
  • You have no history of other brain or nervous system diseases (a past stroke is okay if it has fully resolved with no remaining symptoms)
  • You have no history of lung or breathing diseases
  • You have no history of surgery, cancer, or radiation treatment involving the head or neck area
  • You are currently eating or drinking something by mouth (any amount)
  • You are able to follow simple instructions
  • You are able and willing to give consent, or a legal guardian can give consent on your behalf

Group 2 – Care Partners of People with Alzheimer's Disease:

  • You are the primary caregiver of someone with Alzheimer's disease
  • You are willing to fill out questionnaires and take part in an interview

Group 3 – Healthy Adults Living in the Community:

  • You are 60 years old or older
  • You have no history of brain or nervous system diseases (a past stroke is okay if it has fully resolved with no remaining symptoms)
  • You have no history of lung or breathing diseases
  • You have no history of surgery, cancer, or radiation treatment involving the head or neck area
  • You have never had difficulty swallowing, based on your own report
  • You score at or above the 25th percentile on a memory and thinking test, adjusted for your sex, age, education, and race (confirm with trial site)

Who may not be able to join:

Group 1 – People with Alzheimer's Disease:

  • You are younger than 60 years old
  • You have been diagnosed with a different type of dementia (not Alzheimer's)
  • You have a history of other brain, nervous system, or breathing diseases
  • You have a history of surgery, cancer, or radiation treatment to the head or neck area
  • You are not eating or drinking anything by mouth at all
  • You are unable to follow basic instructions
  • You are unable to give consent and scored below 15 on a specific consent assessment tool, and no legal guardian or healthcare decision-maker is available to consent on your behalf (confirm with trial site)

Group 2 – Care Partners:

  • You are not the main/primary caregiver of someone with Alzheimer's disease
  • You are unwilling to complete questionnaires or take part in an interview

Group 3 – Healthy Adults:

  • You are younger than 60 years old
  • You have a history of brain or nervous system disease
  • You have a history of lung or breathing disease
  • You have a history of surgery, cancer, or radiation treatment to the head or neck area
  • You have had difficulty swallowing in the past
  • You score below the 25th percentile on a memory and thinking test, adjusted for your sex, age, education, and race (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 June 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
21 April 2025
Est. completion
1 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Swallowing safety

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov