Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 40 and 75 years old
- People who have knee osteoarthritis with pain symptoms rated between 3 and 8 on a standard pain scale
- People where only one knee is affected by symptoms
- People whose knee cartilage damage has been confirmed by X-ray or MRI scan, at a moderate level of severity (confirm with trial site)
- People who have already tried at least one course of treatment — such as medication, physiotherapy, or joint injections — without enough relief from symptoms
- People whose recent blood test results show a haemoglobin level above 11 g/dl and a platelet count above 150,000 per mm³
- People who are willing and able to attend follow-up appointments throughout the trial
- People who have signed a consent form agreeing to take part
Who may not be able to join:
- People who are unable to give their own consent to participate
- People who have had an injection of any substance into the affected joint in the past 6 months
- People who have had knee surgery in the past 12 months
- People who have or have had a cancerous condition
- People who have a rheumatic disease
- People who have diabetes that is not well controlled
- People who have a blood disorder affecting clotting
- People who take blood-thinning or anti-clotting medication that cannot be safely stopped at the time of blood collection
- People who have a thyroid condition that is not well managed
- People who have problems with alcohol, drug, or medication misuse
- People with a Body Mass Index (BMI) over 35
- People who have taken anti-inflammatory pain medicines (such as ibuprofen or similar) in the 3 days before their blood sample is taken
- People with a heart or cardiovascular condition for which having 30 to 60 ml of blood drawn would not be safe
- People whose recent blood test shows haemoglobin below 11 g/dl or platelets below 150,000 per mm³
- Women who are pregnant or of childbearing potential
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Davide Reale, MD, Istituto Ortopedico Rizzoli - Argenta
Phone: 0516366567
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.