Printed from Voxsanity (voxsanity.com.au) — NCT06687772 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
Back to Lymphoma
Phase 2 Lymphoma Trial, Recruiting
NCT06687772
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been newly diagnosed with a type of blood cancer called diffuse large B-cell lymphoma, large B-cell lymphoma that developed from a slower-growing lymphoma, or high-grade B-cell lymphoma (note: a specific type called Richter's transformation is not eligible, but lymphoma that has spread to the brain and spinal cord may be eligible).
- Your doctor has determined you are at high risk of the cancer spreading to the brain and spinal cord, based on factors such as: a risk score of 4 or higher on a standard assessment tool, or cancer involvement in the kidneys, adrenal glands, testicles, breast, ovaries, uterus, skin, bone marrow, heart muscle, areas near the brain/spinal cord, or the brain/spinal cord itself.
- You are planning to receive or are currently receiving a full course of chemotherapy aimed at curing the cancer, and have not yet completed more than 2 rounds of it at the time of joining the trial.
- You are between 18 and 75 years old.
- You are able to understand and agree to the study terms by signing a consent form (a legal representative may do this on your behalf if needed).
- You are currently undergoing the chemotherapy treatment described above (this applies at a later stage of joining the trial).
- Your general health and ability to carry out daily activities meets a certain minimum standard, as assessed by your doctor (confirm with trial site).
- A scan performed partway through your chemotherapy shows the cancer is not getting worse, and your doctor agrees you are suitable for a stem cell transplant using your own cells.
- If you could become pregnant or father a child, you must agree to use reliable contraception during treatment and for a set period afterward (6 months for women, 12 months for men after certain medications; confirm with trial site for details).
Who may not be able to join:
- Your lymphoma has come back or stopped responding to treatment (however, prior treatment for a slower-growing lymphoma that later transformed is allowed).
- You have been diagnosed with primary CNS lymphoma (a type of lymphoma that started in the brain or spinal cord).
- You have another cancer (past or current) that your doctor believes could interfere with your safety or the results of this trial.
- You are currently taking part in another clinical trial using an experimental treatment.
- You have had a serious allergic reaction to medications similar to the ones used in this study (thiotepa or carmustine) (confirm with trial site).
- You are currently pregnant or breastfeeding, or are unable to provide a negative pregnancy test within 7 days before starting treatment.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.
GP referral letter
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Trial details
Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
16 January 2025
Est. completion
31 July 2027
Where this trial is recruiting
🇺🇸 United States
Primary endpoints
Feasibility of treatment
Can't join this trial?
Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.