Crohn's Disease and Colitis Trial, Recruiting NCT06691061 Sponsor: Humanitas Clinical and Research Center Condition: Crohn's Disease and Colitis
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Crohn's Disease and Colitis Trial, Recruiting

NCT06691061
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with ulcerative colitis (a type of inflammatory bowel disease) according to current European medical guidelines
  • People who are 18 years of age or older
  • People who are able to understand and agree to participate in the study
  • People whose ulcerative colitis is currently active at the time of joining the trial
  • People who are starting one of the following medications as their second treatment option: vedolizumab, ustekinumab, or a JAK inhibitor (tofacitinib, upadacitinib, or filgotinib)
  • People who have previously been treated with at least one anti-TNF medication approved for ulcerative colitis (such as infliximab, adalimumab, or golimumab)
  • People who have not previously been treated with vedolizumab, ustekinumab, or any JAK inhibitor
  • People who are able to attend at least one follow-up visit after joining the trial

Who may not be able to join:

  • People diagnosed with Crohn's colitis, unclassified inflammatory bowel disease, or other inflammatory conditions of the digestive system
  • People under 18 years of age
  • People who are unable to give informed consent to participate
  • People whose ulcerative colitis is severely active and requires hospital admission at the time of joining
  • People who have never been treated with an anti-TNF medication before
  • People who have previously been treated with targeted medications for ulcerative colitis other than anti-TNF medications
  • People whose treatment with ustekinumab or a JAK inhibitor was given at a dose or schedule that does not follow the standard approved guidelines for ulcerative colitis (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +39 02 8224 5555

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Humanitas Clinical and Research Center
Registry
ClinicalTrials.gov
Start date
1 August 2023
Est. completion
31 December 2024

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Clinical and endoscopic effectiveness of the three treatments

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov