Phase 2 Type 1 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People with obesity, meaning a Body Mass Index (BMI) between 30 and 50 kg/m², as measured at the screening appointment.
• People who have tried at least once to lose weight through lifestyle changes (such as diet and exercise) without success.
• People who have had Type 2 diabetes for at least 6 months before screening, with blood sugar levels (HbA1c) in a specific range (6.0%–9.5%), and who have been on a stable diabetes medication routine for at least 3 months — this applies to certain parts of the trial only (confirm with trial site).
• People who are willing and able to follow all study requirements, including keeping to a stable diet and exercise routine for the whole duration of the trial.
• People who have no significant abnormal health findings at screening that could affect their safety or the study results, as judged by the study doctor.
• People of childbearing potential who agree to use highly effective contraception during the study and for at least 90 days after the study ends or the last dose of study medication (whichever is later), and who agree not to donate sperm or eggs during that same period.

Who may not be able to join:

• People who have lost or gained more than 5% of their body weight in the 3 months before screening.
• People who have used GLP-1 receptor agonist medications (such as liraglutide or semaglutide) for any reason in the 6 months before screening.
• People who have used other prescription or over-the-counter weight loss medications or supplements (such as naltrexone/bupropion, orlistat, or phentermine/topiramate) in the 3 months before screening.
• People whose obesity is considered by the study doctor to be caused by a medication, a single-gene condition, or a hormonal disorder (conditions other than polycystic ovary syndrome).
• People who have previously had surgery or a medical device used to treat obesity.
• People who have used medications strongly linked to weight gain in the 3 months before screening.
• People with Type 1 diabetes.
• People with a history of an overactive thyroid, or whose thyroid hormone levels fall outside a specific range at screening.
• People with significant disease affecting major organs (confirm with trial site for specific details).

Important: Always verify eligibility with the trial site directly before applying.