Phase 2 Lymphoma Trial, Recruiting NCT06701357 Sponsor: Ruijin Hospital Condition: Lymphoma
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Phase 2 Lymphoma Trial, Recruiting

NCT06701357
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with diffuse large B-cell lymphoma (a type of blood cancer) confirmed by a tissue sample, and whose cancer cells test positive for a protein called CD20
  • People whose cancer cells show high levels of two specific proteins — MYC (at 40% or more) and BCL2 (at 50% or more) — measured by standard laboratory testing
  • People aged 18 to 75 years old
  • People whose general physical health is rated at 0, 1, or 2 on a standard medical scale used to measure how much a condition affects daily activities (confirm with trial site)
  • People with no previous or current history of any other cancer
  • People whose treating doctor judges them to have a life expectancy of at least 6 months
  • People (or their legal representative) who are willing and able to provide written consent before any trial-related procedures begin
  • People with an International Prognostic Index (IPI) score greater than 1 — a scoring system doctors use to assess lymphoma risk (confirm with trial site)

Who may not be able to join:

  • People who have previously received any chemotherapy or other systemic or local cancer treatment
  • People who have previously had an autologous stem cell transplant (a procedure using the patient's own stem cells)
  • People with a history of another cancer, except for certain non-invasive skin or cervical cancers
  • People with uncontrolled heart or blood vessel disease, blood clotting disorders, connective tissue diseases, or serious active infections
  • People whose lymphoma started in the central nervous system (brain and spinal cord)
  • People whose heart pumping function (left ventricular ejection fraction) is at or below 50%
  • People with certain abnormal blood test results at the time of screening, unless those results are caused by the lymphoma itself — including low white blood cell or platelet counts, or elevated liver or kidney markers above specified limits
  • People with any other ongoing medical condition that the trial doctor believes would interfere with participation
  • People with a mental illness or any condition that may make it difficult to follow the trial procedures fully
  • Women who are pregnant or breastfeeding
  • People living with HIV
  • People with certain results on hepatitis B blood tests may need additional testing, and in some cases the condition would need to reach a specific status before joining would be considered (confirm with trial site for details)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 18917762217

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
10 December 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

CRR(Complete response rate)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov