Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You must be between 25 and 80 years old.
- You must be able to read at roughly a 6th grade level, and have enough work or educational history to show no intellectual disability, as judged by the study team.
- You (or your legal representative) must be willing to sign a consent form after the study has been fully explained to you — this may be done by phone or online.
- You must be willing to have an MRI scan and either a lumbar puncture (spinal tap) or a series of PET scans.
- If you are between 45 and 80 years old, you must have a "study partner" (such as a family member or close friend) who is willing to take part in the study and who can also read at roughly a 6th grade level.
Who may not be able to join:
- People who have a significant or unstable brain or nervous system condition, such as a history of multiple head injuries, stroke, multiple sclerosis, or Parkinson's disease.
- People who have a significant or unstable mental health condition.
- People who have had issues with alcohol or drug dependency or abuse within the last 2 years.
- People whose screening scores for anxiety or depression are above a certain level (confirm with trial site).
- People who have a serious ongoing medical condition that the study doctor believes would put them at risk by participating.
- People who cannot have a 3T MRI scan — for example, due to certain implanted medical devices or other reasons that make MRI unsafe or unsuitable for them.
- People who have been diagnosed with most types of cancer in the past 5 years — though some exceptions may apply, such as certain skin cancers or early-stage cervical cancer (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Heather E Whitson, MD, MHS, Duke University
Phone: 919-660-2340
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of participants enrolled who are aged 25 to 44 with normal cognition; Number of participants enrolled who are aged 45 to 80 with normal cognition; Number of participants enrolled who are aged 45 to 80 with mild cognitive impairment (MCI); Number of participants enrolled who are aged 45 to 80 with dementia
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.