Phase 2 Rare Disease Trial, Recruiting NCT06706076 Sponsor: BlossomHill Therapeutics Condition: Rare Disease
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Phase 2 Rare Disease Trial, Recruiting

NCT06706076
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older (or considered a legal adult)
  • You have been formally diagnosed with advanced or spreading non-small cell lung cancer (NSCLC) that has specific gene mutations called EGFR or HER2 mutations in certain parts of the gene
  • You have already received standard treatments for your condition
  • You have at least one measurable area of cancer outside the brain that can be tracked during the trial
  • Your overall health and ability to carry out daily activities meets a certain minimum level (confirm with trial site)
  • You are expected to live for at least 3 months or more
  • Your blood, liver, and kidney functions are at acceptable levels (confirm with trial site)

Who may not be able to join:

  • You have been diagnosed with another cancer in the past 2 years
  • Your cancer has other specific gene changes (such as certain MET gene amplifications) or has changed into a different type of cancer (such as small cell lung cancer)
  • You still have unresolved side effects from previous cancer treatments
  • You have a significant medical condition that is not well controlled, such as an active infection
  • You have a history of a lung condition called interstitial lung disease, caused by any reason
  • You have had a serious heart or blood vessel event in the past 6 months, or have a significant history of major organ problems (confirm with trial site)
  • You are currently taking part in another clinical trial and receiving an experimental treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: (858) 732-3880

Australian sites

Austin Health, Heidelberg, Victoria
Peter MacCallum Cancer Centre, Melbourne, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
BlossomHill Therapeutics
Registry
ClinicalTrials.gov
Start date
9 January 2025
Est. completion
31 January 2029

Where this trial is recruiting

🇦🇺 Australia 🇨🇦 Canada Hong Kong 🇯🇵 Japan 🇲🇾 Malaysia 🇸🇬 Singapore 🇰🇷 South Korea 🇹🇼 Taiwan 🇺🇸 United States

2 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Dose-limiting toxicities (DLTs) (Phase 1, Dose Escalation); Recommended Phase 2 dose (RP2D) (Phase 1, Dose Expansion/Optimization); Objective Response Rate (ORR) (Phase 2)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov