Phase 2 Rare Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older (or considered a legal adult)
- You have been formally diagnosed with advanced or spreading non-small cell lung cancer (NSCLC) that has specific gene mutations called EGFR or HER2 mutations in certain parts of the gene
- You have already received standard treatments for your condition
- You have at least one measurable area of cancer outside the brain that can be tracked during the trial
- Your overall health and ability to carry out daily activities meets a certain minimum level (confirm with trial site)
- You are expected to live for at least 3 months or more
- Your blood, liver, and kidney functions are at acceptable levels (confirm with trial site)
Who may not be able to join:
- You have been diagnosed with another cancer in the past 2 years
- Your cancer has other specific gene changes (such as certain MET gene amplifications) or has changed into a different type of cancer (such as small cell lung cancer)
- You still have unresolved side effects from previous cancer treatments
- You have a significant medical condition that is not well controlled, such as an active infection
- You have a history of a lung condition called interstitial lung disease, caused by any reason
- You have had a serious heart or blood vessel event in the past 6 months, or have a significant history of major organ problems (confirm with trial site)
- You are currently taking part in another clinical trial and receiving an experimental treatment
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: (858) 732-3880
Australian sites
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
2 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
Dose-limiting toxicities (DLTs) (Phase 1, Dose Escalation); Recommended Phase 2 dose (RP2D) (Phase 1, Dose Expansion/Optimization); Objective Response Rate (ORR) (Phase 2)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.